homemade prototype of a disposable flow reactor
homemade prototype of a disposable flow reactor
Our lab is equipped with benchtop flow reactors adaptable for many reaction and processes, including photochemical transformations and reactions where reagents or products are solid suspensions. We develop and use flow chemistry platforms and methods for the synthesis of functionalized nanosystems and the batch-to-flow transposition of active pharmaceutical ingredients syntheses, including those that are distressing or unsafe. Running a chemical reaction in a confined environment, typical of the channels network of micro/meso flow reactors, greatly improves the control over mixing, temperature and reaction time, enhances the sustainability of the syntheses and reduces the user's exposure to potentially toxic compounds. The effortless scale-up characteristic of continuous-flow processing makes the optimized syntheses ready for industrial consideration.Â
We prepare molecular structures to develop new organic functional materials and medicinal compounds. Our group has a long history of functionalizing carbon nanostructures ([60]fullerene, carbon nanotubes, graphene-based materials) and p-conjugated molecular architectures for solar energy conversion. Our aim also is to discover drug-like compounds to fight cancer. In this connection, we are part of a team where molecular modeling, virtual screening, organic synthesis, and biological testing mutually guide the drug discovery process. We try to establish synthetic protocols that are safe and environmentally friendly through the batch-to-flow transposition of syntheses for process optimization and scale-up, and by searching for renewable resources as an alternative to petrochemical intermediates.