PhD student
Agnese Pavan's Thesis project develops multifunctional, biodegradable hydrogels designed to tackle key agricultural challenges: water scarcity, soil nutrient depletion, and heavy metal contamination. By reinforcing the hydrogel matrix with nanofillers (including conductive MXenes), secondary polymers, and functional molecules like plant growth regulators and chelating agents, the aim is to create smart materials capable of controlled water/nutrient release and real-time soil sensing. Green chemistry principles guide the entire synthesis process.
PhD student
Matteo Benetazzo's thesis project focuses on optimizing HSP90α (Heat Shock Protein 90α) inhibitors as senolytic agents. Building on prior work identifying compound K5, a xanthine-based HSP90α inhibitor with senolytic activity, the study aims to generate more potent derivatives through structural optimization. Using MIF (Molecular Interaction Fingerprint) analysis, molecular docking, and Lambda Dynamics simulations, a focused library of K5 analogues was designed and evaluated. Four of thirteen synthesized derivatives showed greater potency than K5 in inhibiting HSP90α, as measured by HSF1 (Heat Shock Factor 1) nuclear relocalization in senescent cells, establishing them as promising candidates for next-generation senolytic therapy.
Giorgia Possamai (2000) - Electrolux Italia - Project leader
Raffaele Riccò (2003) - Concrete4change - Carbon capture chemist
Graziano Fabbrini (2004) - FIS Fabbrica Italiana sintetici - API production manager
Elena Brasola (2006) - FIS Fabbrica Italiana sintetici - IP specialist
Paola Donnola (2009) - Galentis - QC team leader
Emiliano Rossi (2011) - FIS Fabbrica Italiana sintetici - R&D team leader
Simone Silvestrini (2011) - Procter & Gamble - Group scientist
Christian Corrado De Filippo (2014) - FIS Fabbrica Italiana sintetici - R&D team leader
Andrea Faresin (2018) - alpinestars - Junior report analyst
Meng Zheng (2018) - Quingdao Haiwan Science&Technology Institute - Research engineer
Stefano Schergna (2001-2003)
Davide Dattilo (2005-2007) - Process Scientist at Suss Microtec Lithography
Prasenjit Maity (2008) - Professor at National Forensic Science University, Bombay
Edmondo Benetti (2011-2012) - Full professor at University of Padova
Simone Silvestrini (2012) - Procter & Gamble - Group scientist
Amanda Evans (2013) - Scientists in the Biosciences Division at Los Alamos National Laboratory
Mina Roudgar (2013) - Project Manager at Janssen Pharmaceutical Companies
Hyacintha Lobo (2013-2015) - Technical Advisor at ROBIC, India
Alberto Ongaro (2025) - RTDa Researcher at University of Ferrara